Scientists are working on hard on making a kind of booze that won't give you hangovers at all. Does this sound like a good idea? Weren't hangovers supposed to be the kind of thing that reminded you why you shouldn't party too hard in the first place?

Anyway, that's what scientists are doing.

University of Illinois scientists have engineered a “jailbreaking” yeast that could greatly increase the health benefits of wine while reducing the toxic byproducts that cause your morning-after headache.

Recently scientists have developed a “genome knife” that cuts across multiple copies of a target gene in the genome very precisely–until all copies are cut. Jin’s group has now used this enzyme, RNA-guided Cas9 nuclease, to do precise metabolic engineering of polyploid Saccharomyces cerevisiae strains that have been widely used in the wine, beer, and fermentation industries.

The possibilities for improved nutritive value in foods are staggering, he said. “Wine, for instance, contains the healthful component resveratrol. With engineered yeast, we could increase the amount of resveratrol in a variety of wine by 10 times or more. But we could also add metabolic pathways to introduce bioactive compounds from other foods, such as ginseng, into the wine yeast.”

Another benefit is that winemakers can clone the enzyme to enhance malolactic fermentation, a secondary fermentation process that makes wine smooth. Improper malolactic fermentation generates the toxic byproducts that may cause hangover symptoms, he said.

Which means, no more this: