Cannabidiol (CBD) is now sold in many different forms, sometimes to promote unique therapeutic benefits, other times just to improve accessibility. Products made from this medicinal, but non-psychoactive part of cannabis and hemp can be used by all age groups, and to naturally treat a broad range of conditions.
The best-known way of taking CBD is in a tincture oil.
The healthiest way to get CBD into the system, tinctures are also offer fast speed of delivery. CBD oil wholesale has been given to children suffering from extreme and typically untreatable forms of epilepsy, those struggling with chronic pain and also people afflicted with anxiety.
CBD-isolate oil v full-spectrum CBD oil
The legal CBD industry consists of products made using industrial hemp extracts. Some products are made using a pure CBD extract, known as an isolate. Others are manufactured by taking the full extract of the plant, which may contain traces of other cannabinoids and terpenes, and up to 0.3 percent tetrahydrocannabinol (THC).
People who are conscious about taking any amount of THC tend to take CBD-isolate oil, as it guarantees that they will have no issues with even the strictest of drugs tests. However, many prefer full-spectrum CBD, as an extract with a full array of plant compounds can have a greater therapeutic effect – this is the result of synergy, known in this case as the 'entourage effect'.
There are reasons for taking both CBD-isolate and full-spectrum CBD oil, hence why there is a high demand for both.
Therapeutic uses for CBD oil
In this section, we will explain how CBD tincture oils especially can be taken to relieve symptoms from the following illnesses.
CBD oil is taken sublingually, under the tongue. Product guidelines usually recommend holding the CBD for a couple of minutes before swallowing, as this allows for maximum absorption of cannabinoids.
Patients have been left with inferior treatment for anxiety, with SSRI drugs not working anywhere near quickly enough. In addition to promoting calming GABA neurotransmitters in the brain, the appeal of CBD oil for anxiety is that the benefits are observable just a few minutes after consumption.
This efficiency means that CBD oil can essentially be used to reduce anxiety on-demand. The best times to dose up is when an anxiety attack is beginning or can be anticipated.
The endocannabinoid system (ECS) is implicated in pain perception, which is understandable as it’s part of the central nervous system. The ECS controls pain at the CB1 receptor, with agonists such as anandamide working as natural analgesics.
However, the body produces a limited amount of anandamide, and those who don’t make enough of it need external help to restore ECS balance and homeostasis.
CBD can provide that assistance, although indirectly. The cannabinoid doesn’t stimulate anandamide production, but increases levels of the endocannabinoid by stopping it from being broken down at the FAAH enzyme.
The condition fibromyalgia brings about a complex list of symptoms, which affect our mental and physical functioning. Officially, the cause of the debilitating illness is unknown, but it appears more and more likely to be due to ECS dysfunction – a disorder referred to as Clinical Endocannabinoid Deficiency.
With fibromyalgia patients creating fewer endocannabinoids than the average healthy person, the system cannot regulate itself, hence leading to higher sensitivity to pain, depressed mood and reduced cognition (or 'fibro fog').
As the cause behind fibromyalgia has, until now, been a mystery, treatments for the condition have also been substandard. However, correction endocannabinoid deficiency is as simple as boosting endocannabinoids like anandamide and 2-AG. We know that CBD oil can help here by preventing anandamide degradation.
Poor cognition due to heavy cannabis use
Cannabis has become more potent in the 21st century. On a chemical level, this is because of rising quantities of THC, and the falling concentrations of CBD in strains. As this is a recent development, we are only beginning to understand the implications of this drastic change. But research is showing that heavy and sustained intake of THC has a neurotoxic effect on the hippocampus, causing structural changes which can lead to memory loss and low motivation.
However, CBD is neuroprotective, and the neurogenesis that the compound triggers in the hippocampus helps to regrow this section of the brain. A 2018 study found that the more a person consumed cannabis, the more beneficial a CBD treatment plan could be. CBD oil is one of many wholesale CBD products that helps restore normal brain activity in chronic cannabis users.
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